Nadifloxacin IP

Buy Nadifloxacin IP in Mumbai, India

CAS Number:124858‑35‑1

Synonyms: Nadifloxacin; Acuatim; Jinofloxacin; OPC‑7251; 9‑fluoro‑6,7‑dihydro‑8‑(4‑hydroxypiperidin‑1‑yl)‑5‑methyl‑1‑oxo‑1H‑pyrido[3,2,1‑ij]quinoline‑2‑carboxylic acid

Chemical Formula:C₁₉H₂₁FN₂O₄

Molecular Weight:360.38 g/mol

Product Introduction

Off-white crystalline powder (≥98% HPLC/USP). Nadifloxacin is a topical fluoroquinolone antibiotic indicated for acne vulgaris and other bacterial skin infections. It exhibits anti-inflammatory effects and inhibits bacterial DNA gyrase, including MRSA strains.

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Physical & Chemical Properties

Property Value
Appearance Off‑white crystalline powder
Purity ≥98% HPLC/USP
Melting Point 245–247 °C
Solubility Insoluble in water; soluble in DMSO/ethanol
Mechanism of Action Bactericidal via DNA gyrase inhibition; anti‑inflammatory activity

Applications

  • Pharmaceutical API: Topical antibiotic for acne and minor skin infections
  • Formulation aid: Used in creams and gels; standard reference for analytical QC/HPLC

Safety & Handling

  • Generally non-irritant as per SDS; use standard precautions. Store refrigerated at 2–8 °C, protect from light and moisture.

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