Ethyl Cyanoacetate

Buy ethyl cyanoacetate in Mumbai, India

CAS Number:105‑56‑6

Synonyms: Ethyl cyanoacetate; Ethyl 2‑cyanoacetate; Cyanoacetic acid ethyl ester

Chemical Formula:C₅H₇NO₂

Product Introduction

A colorless liquid with a mild, pleasant odor. Ethyl cyanoacetate features both ester and nitrile functional groups, making it a versatile building block for Knoevenagel condensations, heterocycle synthesis, pharmaceutical intermediates, and agrochemical production.

Physical & Chemical Properties

Property Value
Appearance Colorless (slightly straw) liquid
Odor Mild, pleasant
Density @ 25 °C ~1.063 g/mL
Melting Point –22 °C
Boiling Point 208–210 °C
Flash Point (PMCC) >110 °C (~230 °F)
Vapor Pressure @ 25 °C ~1 mm Hg (at 67.8 °C)
Vapor Density ~3.9 × air
Refractive Index (n₂₀ᴅ) ~1.418
Water Solubility @ 20 °C ~20 g/L
Molecular Weight 113.11 g/mol

Applications

  • Knoevenagel condensations: Forms α,β-unsaturated compounds with aldehydes.
  • Pharma/agro intermediates: In heterocycle, barbiturate, vitamin, and nucleotide synthesis.
  • Building block: For ethyl glyoxylate, cyanoacrylate esters, and specialty chemicals.

Reactivity

  • Hydrolyzes under neutral/alkaline conditions; stable in acid.
  • Features reactive nitrile, ester, and acidic methylene sites for broad synthetic utility.
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