Para Toluene Sulfonic Acid

Para Toluene Sulfonic Acid

CAS Number: 104‑15‑4 (anhydrous) / 6192‑52‑5 (monohydrate)

Synonyms: p‑Toluenesulfonic acid; Tosylic acid; PTSA; TsOH; para‑toluenesulphonic acid

Chemical Formula:C₇H₈O₃S (monohydrate adds H₂O)

Molecular Weight:172.20 g/mol (anhydrous); ~190.22 g/mol (monohydrate)

Product Introduction

A white, strongly hygroscopic crystalline solid. p‑TsOH is a strong organic acid (~100 000× stronger than benzoic acid) used as a solid acid catalyst in esterifications, dehydrations, polymerization, and as a pH adjuster in pharmaceutical and fine chemical transformations.

Physical & Chemical Properties

Property Value
Appearance White crystalline powder (monohydrate)
Melting Point 38 °C (anhydrous); 105–107 °C (monohydrate)
Boiling Point ~140 °C @ 20 mmHg
Density ~1.24 g/cm³
Solubility ~67 g/100 mL H₂O; soluble in alcohols, polar solvents
Refractive Index (n₂₀ᴅ) ~1.3825–1.3845
pKₐ –2.8 (strong sulfonic acid)

Applications

  • Acid catalyst in esterification, dehydration, polymerization, benzimidazole formation, trimerizations
  • pH adjuster in pharmaceutical formulations
  • Surfactant/solubilizer in cosmetics and specialty coatings

Safety & Handling

  • Strong acid, skin/eye irritant (GHS H315/H319/H335). Hygroscopic—store airtight below 15 °C. Use PPE, gloves, goggles, and work in well-ventilated areas.
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