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D‑Mandelic Acid

CAS Number: 611‑71‑2

Synonyms: D‑(-)-Mandelic acid; (R)-(-)-Mandelic acid; Amygdalic acid

Chemical Formula:C₈H₈O₃

Product Introduction

D‑Mandelic Acid is a white to light-yellow crystalline α-hydroxy acid derived from bitter almonds. Optically active (>99% ee), it’s used as a chiral building block in pharmaceuticals, cosmetics, and organic synthesis for its antibacterial and antioxidant properties.

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Physical & Chemical Properties

Property	Value
Appearance	White to light-yellow crystalline powder
Purity/Purity (optical)	≥ 99 %, ee ≥ 98 %
Melting Point	~132–135 °C
Density	~1.30 g/cm³
Solubility	Soluble in water, ethanol, acetone, ether
Molecular Weight	152.15 g/mol
Optical Rotation	[α]₂₀ᴅ ~ –153° (c=1, H₂O)

Applications

Chiral resolving agent: Used for enantioseparations in pharmaceuticals.
Pharma intermediate: Building block for antibiotic, antirheumatic, and antispasmodic compounds.
Cosmetics: Functions as mild antioxidant and antibacterial additive.
Analytical/biochemical reagent: Used in research and chemical synthesis.