N-Ethyl Piperazine

N-Ethyl Piperazine

CAS Number:109‑01‑3

Synonyms:1‑Methylpiperazine; N‑Methylpiperazine; p‑Methylpiperazine

Chemical Formula:C₅H₁₂N₂

Molecular Weight:100.16 g/mol

Product Introduction

A clear, colorless, hygroscopic liquid with a fishy-amine odor. A tertiary cyclic diamine and versatile organic intermediate used in pharmaceuticals (cyclizine, sildenafil), gas-scrubbing, surfactants, and textile processing

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Physical & Chemical Properties

Property Value
Appearance Colorless liquid
Odor Fishy/amine-like
Density @ 20 °C ~0.90–0.91 g/cm³
Melting Point –6 °C
Boiling Point ~136–138 °C
Flash Point ~39–42 °C
Vapor Pressure @ 20 °C ~0.9 kPa (6.7 mm Hg)
Solubility Completely miscible in water
pH (50 g/L in water) ~11–12
Explosion Limits ~1.2–9.9 % v/v

Applications

  • Pharma: intermediate in active drugs (cyclizine, meclizine, sildenafil)
  • Chemical intermediate:gas scrubbing agents, surfactants, textile chemicals
  • Reagent:used in lithium salts for aldehyde protection and other specialty syntheses

Safety & Handling

  • Flammable; corrosive; vapor may irritate eyes and respiratory system.
  • GHS: H302/H312/H318/H315; use PPE, ventilated area, store away from ignition and moisture.

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