2,3‑Dimethyl‑4‑Nitropyridine‑N‑Oxide

2,3‑Dimethyl‑4‑Nitropyridine‑N‑Oxide

CAS Number:37699‑43

Synonyms:4‑Nitro‑2,3‑lutidine N‑oxide; 2,3‑dimethyl‑4‑nitropyridine 1‑oxide

Chemical Formula:C₇H₈N₂O₃

Product Introduction

A yellow-to-orange crystalline solid, 2,3‑Dimethyl‑4‑Nitropyridine‑N‑Oxide is a nitro-substituted pyridine derivative featuring an N‑oxide. It serves as a reactive intermediate in heterocyclic chemistry and is used in oxidation, cyclization, and nucleophilic substitution reactions.

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Physical & Chemical Properties

Property Value
Appearance Yellow–orange crystalline solid
Purity ≥ 97–98 %
Melting Point 92–98 °C
Molecular Weight 168.15 g/mol
Molecular Formula C₇H₈N₂O₃
Density (est.) ~1.3 g/cm³

Applications

  • Organic synthesis intermediate: Nitro and N‑oxide functionalities enable further conversion to aminopyridines, pyridones, and heterocycles
  • Medicinal chemistry: Used in the development of drug candidates and fine chemicals for unique electronic behavior
  • Reagent in heterocyclic frameworks: Ideal for nucleophilic, cyclization, or reduction transformations

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