3-Fluorobenzenesulfonyl Chloride

3-Fluorobenzenesulfonyl Chloride

CAS Number:701‑27‑9

Synonyms: 3‑Fluorobenzenesulfonyl chloride; m‑Fluorobenzenesulfonyl chloride

Chemical Formula::C₆H₄ClFO₂S

Product Introduction

A colorless-to-yellow liquid aryl sulfonyl chloride, used in pharmaceutical and fine chemical synthesis. It features a highly reactive sulfonyl chloride group ideal for coupling reactions.

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Physical & Chemical Properties

Property Value
Appearance Clear to pale yellow liquid
Purity ≥ 96–98 % (GC)
Molecular Weight 194.60–194.61 g/mol
Density @ 25 °C ~1.46 g/cm³
Boiling Point ~231–232 °C (literature)
Refractive Index (n₂₀ᴅ) ~1.529
Flash Point Not applicable (liquid)

Applications

  • Coupling agent: Used to introduce –SO₂Cl into phenolic and amine substrates.
  • Pharma & fine-chem synthesis: Key intermediate in heterocycle and drug development.
  • Specialty reagents: Useful in preparing aryl sulfonamides and pyrroles.

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